Vulvodynia: Causes, Symptoms, and Treatments
Women with vulvodynia have chronic vulvar pain with no known cause. Until recently, doctors didn’t recognize this as a real pain syndrome. Even today, many women do not receive a diagnosis. They may also remain isolated by a condition that is not easy to discuss. Researchers are working hard to uncover the causes of vulvodynia and to find better ways to treat it.
Types of Vulvodynia
Vulvodynia affects the vulva, the external female genital organs. This includes the labia, clitoris, and vaginal opening.
There are two main subtypes of vulvodynia:
- Generalized vulvodynia ispain in different areas of the vulva at different times. Vulvar pain may be constant or occur every once in a while. Touch or pressure may or may not prompt it. But this may make the pain worse.
- Vulvar vestibulitis syndrome is pain in the vestibule. This is the entrance to the vagina. Often a burning sensation, this type of vulvar pain comes on only after touch or pressure, such as during intercourse.
Possible Causes of Vulvodynia
Doctors don’t know the causes of vulvodynia. And there is no evidence that infections, such as sexually transmitted diseases, cause vulvodynia.
Researchers are trying to find the causes of vulvodynia. They may include:
- Nerve injury or irritation
- Abnormal response in vulvar cells to an infection or trauma
- Genetic factors that make the vulva respond poorly to chronic inflammation
- Hypersensitivity to yeast infections
- Muscle spasms
- Allergies or irritation to chemicals or other substances
- Hormonal changes
- History of sexual abuse
- Frequent antibiotic use
Women with Vulvodynia: Who Has It?
A woman of any age, beginning in her teen years, may have vulvodynia. There is no consensus on how many women have vulvodynia. Estimates of women with vulvodynia range from 200,000 to 6 million. Once thought to mainly affect whites, African-American and Hispanic women are now known to be equally affected.
The Physical and Emotional Impact of Vulvodynia
Vulvodynia can have a huge impact on a woman's life. It can impair her ability to have sex, exercise, socialize, or work. A National Institutes of Health (NIH) study showed that most women with vulvodynia feel “out of control,” unable to have sexual intercourse, and unable to fully enjoy life. If this is true for you, seek the support you need.
Signs and Symptoms of Vulvodynia
Lasting months to years, symptoms of vulvodynia usually begin suddenly.
Common Symptoms of Vulvodynia
These are the most common symptoms of vulvodynia:
- Burning, stinging, or rawness
- Aching, soreness, or throbbing
- Itching
A burning pain is the single most common symptom of vulvodynia. Some women describe it as a knife-like pain or like an acid poured on the skin.
Although the vulva usually appears normal, it may look a bit inflamed or swollen.
WebMD Medical Reference
VIVELLE-DOT (estradiol transdermal system) IS AVAILABLE BY PRESCRPTION ONLY.
INDICATION
Vivelle-Dot is used after menopause to: reduce moderate to severe hot flashes; treat moderate to severe dryness, itching and burning in or around the vagina; help reduce your chances of getting osteoporosis (thin weak bones); and treat certain conditions in which a young woman's ovaries do not produce enough estrogens naturally. Vivelle-Dot 0.025 mg/day is only used to prevent osteoporosis from menopause. If you use Vivelle-Dot only to treat your dryness, itching, and burning in and around your vagina or if you use Vivelle-Dot only to prevent osteoporosis from menopause, talk with your healthcare professional about whether a different treatment or medicine without estrogens might be better for you.
IMPORTANT SAFETY INFORMATION
Estrogens increase the chances of getting cancer of the uterus (womb). Report any unusual vaginal bleeding right away while you are taking estrogens. Vaginal bleeding after menopause may be a warning sign of cancer of the uterus (womb).
Do not use estrogens with or without progestins to prevent heart disease, heart attacks, or strokes. Using estrogens with or without progestins may increase your chances of getting heart attacks, strokes, breast cancer, and blood clots. Using estrogens with progestins may increase your risk of dementia (decline in memory and thinking skills).
Vivelle-Dot should not be used if you have unusual vaginal bleeding; currently have or have had certain cancers, including cancer of the breast or uterus; had a stroke or heart attack in the recent past (for example, in the past year); currently have or have had blood clots; currently have or have had liver problems; or think you may be, or know that you are, pregnant.
The most common side effects that may occur with Vivelle-Dot are headache, breast tenderness, and back pain.
You and your healthcare professional should talk regularly about whether you still need treatment with Vivelle-Dot.
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.
Please see Full Prescribing Information for Vivelle-Dot.

