Women's Weight Tied to Healthy Aging
Study Shows the More Weight Gained From Ages 18 to 50, the Lower the Odds of Being Healthy at 70
Sept. 29, 2009 -- For women, the odds of being healthy at age 70 are best
for those who don't gain a lot of weight between ages 18 and 50 and who aren't
obese at 50.
That news appears in the "Online First" edition of BMJ.
But millions of middle-aged women are overweight and obese, and they can't
go back in time to change that. Researcher Qi Sun, MD, of the nutrition
department at the Harvard School of Public Health, doesn't want those women to
give up on the possibility of healthy aging.
"The key message from our paper is that to enjoy a healthy yet long life,
women need to maintain a healthy body weight throughout adulthood," Sun tells
WebMD in an email. "Meanwhile, I believe it is never too late to take
initiatives to lose weight (in a safe and healthy way) to maximize the
probability to achieve healthy survival," Sun writes.
Sun points out that being physically active, at any weight, is a healthy
"The bottom line is women who are already age 50, no matter what [their]
current weight is, can still benefit from physical activity to increase their
odds of having wonderful health at later life," Sun writes. "Of course, the
best way to maximize the probability of healthy survival is to maintain at
least moderate levels of physical activity AND a healthy body weight throughout
Tracking Healthy Survivors
Sun's study focuses on "healthy survivors." That's the term Sun and
colleagues coined for women they studied who lived to age 70 without any of the
- Cancer (except nonmelanoma skin cancer)
- Heart attack
- Coronary artery bypass
- Congestive heart failure
- Kidney failure
- Chronic obstructive pulmonary disease (COPD)
- Parkinson's disease
- Multiple sclerosis
- Amyotrophic lateral sclerosis (ALS, or Lou Gehrig's disease)
- Major impairment of mental skills
- Major limitation of physical function
- Mental health that's less than good (based on scores from a mental health
Data came from a long-term health study of 121,700 female U.S. nurses.
The women answered questions about their height, weight, health, and
lifestyle every two years for decades, starting in 1976, when they were 30-55
About 17,000 women were still alive, with enough data for Sun's team to
study, at age 70.
Only 10% of those women qualified as healthy survivors.
Weight and Healthy Aging
Women who were obese at age 50 were 79% less likely than women with a normal
BMI at that age to be healthy survivors.
What had happened to the women's weight between age 18 and 50 mattered
Women who were overweight (but not necessarily obese) at age 18, and who
gained at least 10 kilograms (about 22 pounds) by age 50, had the worst odds of
becoming a healthy survivor. Only 18% of those women became healthy
The more weight the women gained between the ages of 18 and 50, the less
likely they were to become healthy survivors.
The study doesn't prove that the women's weight affected their survival.
Observational studies, like this one, don't prove cause and effect. And it's
possible that the nurses in the study don't represent all women.
However, the results held when the researchers adjusted for these factors:
women's age upon enrolling in the study; level of education; marital status;
husband's level of education; hormone use after menopause; smoking; various
diet patterns; family history of heart disease, diabetes, or cancer; and