How It Feels
If you have not had any pain medicine, you may feel a sharp
cramp as the tool is guided through your cervix. You may feel more cramping
when the biopsy sample is collected. Most women find that the cramping feels
like a really bad menstrual cramp.
Some women feel dizzy and sick to their stomachs. This is called
vasovagal reaction. This feeling will go away after
An endometrial biopsy usually causes some vaginal bleeding. You
can use a pad for the bleeding or spotting.
Dilation and curettage (D&C)
If general anesthesia is used during a D&C, you will be
asleep and feel nothing. After the test, you will feel sleepy for a few hours.
You may be tired for a few days after the test. You may also have a mild sore
throat if a tube (endotracheal tube, or ET) was placed in your throat to
help you breathe during the test. Using throat lozenges and gargling with warm
salt water may help relieve your sore throat.
There is a small chance that the cervix or uterus could be
punctured during the biopsy. Bleeding or a pelvic infection is also
After the test
You may feel some soreness in your vagina for a day or two. Some
vaginal bleeding or discharge is normal for up to a week after a biopsy. You
can use a sanitary pad for the bleeding. Do not do strenuous exercise or heavy
lifting for one day after your biopsy. Do not have sex, use tampons, or douche until the spotting stops.
Follow any instructions your doctor gave you. Call your doctor if
- Heavy vaginal bleeding (more than a normal
- A fever.
- Bad-smelling vaginal discharge.
An endometrial biopsy is a way for your doctor to take a small
sample of the lining of the uterus (endometrium ). Lab results from a biopsy
may take several days to get back.
No abnormal cells or cancer is found. For women who have
menstrual cycles, the lining of the uterus is at the right stage for the time
menstrual cycle when the biopsy was done.
A noncancerous (benign) growth, called a
polyp, is present.
Overgrowth of the lining of the uterus (endometrial
hyperplasia) is present.
Cancer or cell changes that may lead to cancer are present.
For women who have menstrual cycles, the lining of the
uterus is not at the right stage for the time in the menstrual cycle when the
biopsy was done. More tests may be needed.
What Affects the Test
Reasons you may not be able to have the endometrial biopsy or why
the results may not be helpful include:
- If you are pregnant. An endometrial biopsy is not done during
- If a vaginal or cervical infection is present.
The infection could spread to the uterus if an endometrial biopsy is
- If the endometrial biopsy sample is not large enough to see
abnormal cells. Another test may be needed.