Date-Rape Drugs (GHB, rohypnol)
Date-Rape Drugs
Gamma-hydroxybutyric acid, or GHB, is a hypnotic depressant known on the street by several names: easy lay, Georgia home boy, liquid X, liquid ecstasy, liquid E, grievous body harm, Gib, G-riffic, natural sleep-500, gamma-oh, cherry meth, scoop, soap, salty water, organic Quaalude, fantasy, sodium oxybate, somatomax, and gamma hydrate. GHB is perhaps best known as the date-rape drug.
- What it looks like: GHB usually comes in a liquid form that can be mixed
with other liquids. Recipes for home synthesis are available on the Internet.
3-butyrolactone and 1,4 butanediol are derivatives of GHB that are converted to
GHB after ingestion. They are often purchased by body builders at health food
stores for their purported muscle-building and fat-burning qualities. GHB is
less commonly available in the capsule form.
- What it does: GHB is a depressant similar to gamma-aminobutyric acid. Its
effects range from drowsiness, forgetfulness, and loss of muscle tone to
seizurelike activity, slowed heartbeat and breathing, and coma. The coma lasts
1-2 hours, with full recovery usually occurring by 8 hours. In the date-rape
scenario, it is often slipped into an unwitting victim's drink. By January
2000, the US Drug Enforcement Agency had reported 60 deaths associated with GHB
use. High school kids are using this as an alternative to alcohol. It leaves no
odor for parents to detect, and the effects are gone by the time users return
home from a night out.
- Harmful effects: Effects of the drug begin 15-60 minutes after use and typically last up to 6 hours. It can be detected in the urine up to 12 hours after ingestion. Tolerance (progressive decreased susceptibility to a drug's effects), dependence (compulsion to take a drug to experience its psychic effects or to avoid the discomfort of its absence), and withdrawal reactions have been reported with GHB use. Respiratory depression can be severe enough to require life support on a ventilator or breathing machine until the drug effects wear off.
Rohypnol (generic name, flunitrazepam) a potent benzodiazepine (a class of tranquilizing agents), is known as Mexican Valium, circles, roofies, la rocha, roche, R2, rope, and forget-me pill. It is available in more than 60 countries in Europe and Latin America, where its legitimate use includes preoperative anesthesia. This drug is not available in North America for sale or prescription. It is usually brought into the United States by mail. Florida, California, and Texas are the states that have the most confiscations of rohypnol.
- What it looks like: The pills usually include a single score, the Roche
imprint, and "1;" or "2;" to denote the tablet strength. The
tablets are usually 1 or 2 mg in strength and are relatively cheap at only $5
per pill. Flunitrazepam is 10 times more potent than diazepam (the generic name
for Valium) and is thus considered a cheap high. Rohypnol is odorless and
colorless, making it easy to slip into someone's drink. Rohypnol has been
associated with date rape.
- What it does: Rohypnol in low doses is a sedative and muscle relaxant. In
higher doses, it can cause lack of muscle control, amnesia, loss of
inhibitions, and loss of consciousness. The effects are usually worsened with
alcohol. Sedation occurs within 30 minutes after ingestion, with peak effects
at 2 hours. As little as 1 mg can impair an individual for 8-12 hours.
- Harmful effects: Adverse effects include low blood pressure, dizziness,
confusion, visual disturbances, inability to urinate fully, and, in some users,
aggressive behavior. Dependence on flunitrazepam can occur. Withdrawal produces
symptoms such as headache, tension, extreme anxiety, restlessness, muscle pain,
light sensitivity, numbness and tingling of arms and legs, and even
seizures.
- Detection: Benzodiazepines are easily detectable on most urine drug screens. However, flunitrazepam is used in such small doses and is so rapidly metabolized that it is not detected on standard drug screens, although it can be detected by specialized laboratories.
WebMD Medical Reference from eMedicineHealth
VIVELLE-DOT (estradiol transdermal system) IS AVAILABLE BY PRESCRIPTION ONLY.
INDICATION
Vivelle-Dot is used after menopause to: reduce moderate to severe hot flashes; treat moderate to severe dryness, itching and burning in or around the vagina; help reduce your chances of getting osteoporosis (thin weak bones); and treat certain conditions in which a young woman's ovaries do not produce enough estrogens naturally. Vivelle-Dot 0.025 mg/day is only used to prevent osteoporosis from menopause. If you use Vivelle-Dot only to treat your dryness, itching, and burning in and around your vagina or if you use Vivelle-Dot only to prevent osteoporosis from menopause, talk with your healthcare professional about whether a different treatment or medicine without estrogens might be better for you.
IMPORTANT SAFETY INFORMATION
Estrogens increase the chances of getting cancer of the uterus (womb). Report any unusual vaginal bleeding right away while you are taking estrogens. Vaginal bleeding after menopause may be a warning sign of cancer of the uterus (womb).
Do not use estrogens with or without progestins to prevent heart disease, heart attacks, or strokes. Using estrogens with or without progestins may increase your chances of getting heart attacks, strokes, breast cancer, and blood clots. Using estrogens with progestins may increase your risk of dementia (decline in memory and thinking skills).
Vivelle-Dot should not be used if you have unusual vaginal bleeding; currently have or have had certain cancers, including cancer of the breast or uterus; had a stroke or heart attack in the recent past (for example, in the past year); currently have or have had blood clots; currently have or have had liver problems; or think you may be, or know that you are, pregnant.
The most common side effects that may occur with Vivelle-Dot are headache, breast tenderness, and back pain.
You and your healthcare professional should talk regularly about whether you still need treatment with Vivelle-Dot.
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.
Please see Full Prescribing Information for Vivelle-Dot.

